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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
25.15
Human Site:
S276
Identified Species:
39.52
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
S276
G
K
R
K
R
R
H
S
E
V
E
T
D
S
K
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
S276
G
R
R
K
R
R
H
S
E
V
E
T
D
S
K
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
S276
G
K
R
K
R
K
H
S
E
V
E
T
D
S
K
Dog
Lupus familis
XP_536242
380
42964
S277
G
K
R
K
Q
K
H
S
E
D
D
I
E
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
S285
K
R
K
R
P
K
H
S
G
A
E
S
G
Y
K
Rat
Rattus norvegicus
Q6AYK5
386
43662
S283
K
R
K
R
Q
K
H
S
E
V
E
S
D
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
S287
E
K
R
K
R
K
P
S
E
N
E
T
T
S
K
Chicken
Gallus gallus
XP_420792
364
42082
I257
R
K
R
K
H
K
H
I
E
E
E
P
C
I
T
Frog
Xenopus laevis
NP_001086609
360
41600
A237
R
K
K
K
K
K
H
A
E
D
E
D
E
N
D
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
E230
E
P
D
E
S
L
N
E
E
G
E
E
P
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
E200
T
E
D
A
A
A
E
E
T
S
N
G
V
T
S
Honey Bee
Apis mellifera
XP_623803
246
28455
M165
Q
Q
K
E
N
G
K
M
S
E
K
I
N
N
V
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
T172
A
A
A
K
K
E
T
T
V
A
T
T
A
A
E
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
K453
K
L
K
R
K
R
D
K
D
I
D
T
V
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
K72
G
N
K
K
Q
K
Q
K
Q
Q
Q
K
Q
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
93.3
93.3
60
N.A.
26.6
46.6
N.A.
66.6
40
33.3
13.3
N.A.
0
0
13.3
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
60
93.3
N.A.
73.3
46.6
73.3
26.6
N.A.
13.3
40
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
7
7
0
7
0
14
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
14
0
0
0
7
0
7
14
14
7
27
7
7
% D
% Glu:
14
7
0
14
0
7
7
14
60
14
60
7
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
0
0
7
0
0
7
7
0
7
7
0
0
% G
% His:
0
0
0
0
7
0
54
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
7
0
14
0
14
0
% I
% Lys:
20
40
40
60
20
54
7
14
0
0
7
7
0
0
47
% K
% Leu:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
7
0
0
7
7
0
7
20
7
% N
% Pro:
0
7
0
0
7
0
7
0
0
0
0
7
7
0
0
% P
% Gln:
7
7
0
0
20
0
7
0
7
7
7
0
7
7
7
% Q
% Arg:
14
20
40
20
27
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
0
0
47
7
7
0
14
0
34
7
% S
% Thr:
7
0
0
0
0
0
7
7
7
0
7
40
7
7
7
% T
% Val:
0
0
0
0
0
0
0
0
7
27
0
0
14
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _